TOP-CKD
Help us find more options to treat chronic kidney disease (CKD).
Study overview
Research Topic
Chronic Kidney Disease (CKD)
Compensation
Up to $1,025
What is the purpose of this study?
This study builds on research that has shown the medicine pirfenidone may help prevent kidney scaring (fibrosis) in people with chronic kidney disease (CKD). Pirfenidone is an approved and effective treatment for preventing scaring of the lungs. What we learn may help expand the number of treatment options for people with CKD.
Who can join?
You may be able to join if you...
- Are at least age 21.
- Have a diagnosis of chronic kidney disease (CKD).
- Do not plan to move away from the Bay Area during the next year.
You can't join if you...
- Have autosomal dominant polycystic kidney disease (PKD).
- Use tobacco or vaping products within the last 3 months.
- Have been hospitalized within the past 30 days.
- And other criteria that can be found on clinicaltrials.gov
Frequently asked questions
What will participants be asked to do?
Over the course of the study, you will be asked to:
- Take the study medicine (pirfenidone) or a placebo (pill without medicine) each day for 1 year.
- Have a total of 3 MRI scans of your kidneys. Each scan takes about 30 minutes.
- Meet with the study team at UCSF a total of 17 times over the course of the study. Most visits only take 1 hour.
- Give small samples of blood and urine.
Are there costs?
No. All costs are covered by the study. Deciding whether or not to participate in the study will not affect your insurance or other medical care.
Will I be paid?
Yes. You can receive up to $1,025 for completing all parts of the study.
How will I benefit?
There may be no direct benefit to you for participating. However, researchers hope to learn information about a potential new treatment for persons with chronic kidney disease (CKD), which will help inform treatment of future patients with kidney disease like you.
Who is leading the study?
Dr. Michael Shlipak and Dr. Meyeon Park, and associates from the Department of Medicine, Division of Nephrology at the University of California, San Francisco are conducting the study.
Where can I read more about this study?
More reading can be found on clinicaltrials.gov. We welcome you to reach out to the study team with any other questions or concerns. Their contact information can be found below.
Want more information?
Click below, or you can reach the study team by phone at (415) 502-1886, or email at [email protected].